Trends in Prevalent Cases and Disability-Adjusted Life-Years of Depressive Disorders Worldwide: Findings From the Global Burden of Disease Study From 1990 to 2021.

Depress Anxiety · 2025 · PMC12045679 · PMID 40313474

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0.0013

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a decreasing trendp =0.0013actually significant

Worldwide, a decreasing trend and significant associations between the ASPR and the SDI ( R = −0.22, p =0.0013) and between the ASDR and the SDI ( R = −0.28, p < 0.001) were observed.

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an increasing trendno p-value reported

An exception to this trend was observed in high-SDI regions, where an increasing trend appeared from 1990 to 2019; enormous increase in ASPR and ASDR appeared in all regions from 2020 to 2021, whereas high-SDI regions contributed the largest increase in growth.

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