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Global burden of colon and rectal cancer and attributable risk factors in 204 countries and territories from 1990 to 2021.

BMC Gastroenterol · 2025 · PMC12048922 · PMID 40316922

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a decreasing trendno p-value reported
Conclusion From 1990 to 2021, the global burden of CRC showed a decreasing trend, with the most substantial reductions observed in high-income regions.

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