Transcription blocking properties and transcription-coupled repair of N<sup>2</sup>-alkylguanine adducts as a model for aldehyde-induced DNA damage.

With a 7-fold reduction of the EGFP signal ( p = 2.4 × 10 −10 ) the effect of εG was also highly significant, thereby indicating a clear negative effect on the gene expression ( Fig. 2 C ).

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