The application of this modified protocol was considered acceptable for the testing of the substance, also in view of the highly significant positive response elicited under the study conditions by positive control substances covering both mechanisms implicated in micronucleus formation (clastogenic by mitomycin C and aneugenic by colchicine).
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Safety assessment of the substance N,N'-(2-(4-(2-aminobenzamido)butyl)pentane-1,5-diyl)bis(2-aminobenzamide) for use in plastic food contact materials.
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