Global burden of ischemic stroke in adults aged 60 years and older from 1990 to 2021: Population-based study.

PLoS One · 2025 · PMC12052125 · PMID 40323959

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an increasing trendno p-value reported

Between 1990-2021, the ASPR of High-middle SDI and Middle SDI subgroups showed an increasing trend, while the AAPCs of other subgroups were 0.14 and 0.43, respectively.

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a decreasing trendno p-value reported

Unlike ASPR and ASIR, ASMR and ASDR showed a decreasing trend from year to year over the period 1990–2021, with AAPC -1.62 and -1.42 going down, respectively.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.