iSoMAs: Finding isoform expression and somatic mutation associations in human cancers.

PLoS Comput Biol · 2025 · PMC12052144 · PMID 40053523

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marginally significantno p-value reported

iSoMAs also pinpointed two novel GAS family genes, GAS7 and GAS6 , as SF3B1 targets with high confidence ( GAS7 is marginally significant).

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marginal significanceno p-value reported

Two additional SF3B1 targets in UVM, ADAM12 and GAS8 (growth arrest-specific 8), predicted by iSoMAs with marginal significance level ( S7A Fig ), have also been validated by the qRT-PCR assay. iSoMAs also pinpointed two novel GAS family genes, GAS7 and GAS6 , as SF3B1 targets with high confidence ( GAS7 is marginally significant).

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