For instance, small molecule ISRIB can reverse the effects of eIF2α phosphorylation on translation and regulate the dynamics of stress granules, which may be significant for treating diseases associated with eIF2α phosphorylation, stress granule formation, and cognitive decline [ 134 , 135 ].
← all excerpts
Current perspectives in drug targeting intrinsically disordered proteins and biomolecular condensates.
1
—
—