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Proton Pump Inhibitors Use in Patients With Ischemic Stroke on Dual Antiplatelet Therapy at Low Risk of Upper Gastrointestinal Bleeding.

J Am Heart Assoc · 2025 · PMC12054488 · PMID 39719424

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an increasing trendno p-value reported
20 , 21 Our study, which showed an increasing trend in PPI use despite the absence of clear stroke guidelines, 4 suggests that clinicians may be influenced by the potential benefits of PPI outlined in coronary guidelines. 12 , 13 , 14 , 15 Notably, our findings indicate that PPI use could decrease significant UGIB risk, even in low‐risk groups.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.