Although the meta-analysis revealed a significant difference in CIMT values between AAV patients and healthy controls, individual studies showed non-significant or marginally significant differences This could be due to different factors like level of chronic inflammation in each AAV subtype, methods of CIMT measurements, duration of the AAV, active or inactive stage of the disease, effect of corticosteroids or other immunosuppressants, and other patient’s demographic factors like traditional cardiovascular risk factors.
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Evaluating subclinical atherosclerosis, arterial stiffness, and lipid profile in patients with anti neutrophilic cytoplasmic antibodies associated vasculitis: a systematic review and meta-analysis.
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