Conversely, if both the EAPC estimate and the upper limit of its 95% CI were negative, the ASR was considered to indicate a decreasing trend.
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Global Trends and Regional Differences in the Burden of Infective Endocarditis, 1990-2021: An Analysis of the Global Burden of Disease Study 2021.
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The sentences
When the EAPC and the lower limit of its 95% CI were both positive, the ASR was regarded as displaying an increasing trend.