highly significantp < 0.001
The p values in the graphs are indicated as follows: * p < 0.05 (significant), ** p < 0.01 (highly significant), and *** p < 0.001 (highly significant).
The p values in the graphs are indicated as follows: * p < 0.05 (significant), ** p < 0.01 (highly significant), and *** p < 0.001 (highly significant).
A trend was also confirmed in the COMwC subgroup (+ 58.5%), however, the differences failed to reach significance (8.4 ± 4.3% E+ vs. 5.3 ± 2.0% E− ; p > 0.05).