The association between IL12B gene polymorphisms and psoriasis susceptibility has also been reported in an Egyptian cohort study, in which the rs610604 in the IL12B gene exhibited a highly significant association with psoriasis in patients with early onset of the disease (less than 30 years) ( 92 ).
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Psoriasis: Immunological and genetic blueprints driving pathogenesis and potential for personalized therapies.
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