Novel C-3 and C-20 derived analogs of betulinic acid as potent cytotoxic agents: design, synthesis, <i>in vitro</i> and <i>in silico</i> studies.

RSC Adv · 2025 · PMC12061048 · PMID 40343306

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highly significantno p-value reported

3 Natural products have played a highly significant role as a source of lead molecules for anticancer drug discovery.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Novel C-3 and C-20 derived analogs of betulinic acid as potent cytotoxic agents: design, synthesis, &lt;i&gt;in vitro&lt;/i&gt; and &lt;i&gt;in silico&lt;/i&gt; studies.

The sentences

Novel C-3 and C-20 derived analogs of betulinic acid as potent cytotoxic agents: design, synthesis, <i>in vitro</i> and <i>in silico</i> studies.