Targeted synthesis of a trimethoxyphenyltetrahydropyrimidine analogue designed as a DNA intercalator: <i>in silico</i>, multi-spectroscopic, thermodynamic, and <i>in vitro</i> approaches.

RSC Adv · 2025 · PMC12061050 · PMID 40343313

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highly significantno p-value reported

This information is highly significant for rationally designing anticancer candidates, intending to enhance their activity and selectivity. 4.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Targeted synthesis of a trimethoxyphenyltetrahydropyrimidine analogue designed as a DNA intercalator: &lt;i&gt;in silico&lt;/i&gt;, multi-spectroscopic, thermodynamic, and &lt;i&gt;in vitro&lt;/i&gt; approaches.

The sentences

Targeted synthesis of a trimethoxyphenyltetrahydropyrimidine analogue designed as a DNA intercalator: <i>in silico</i>, multi-spectroscopic, thermodynamic, and <i>in vitro</i> approaches.