Anticoagulant prescribing trends, bleeding events, and reversal agent use in pediatric patients: A retrospective, real-world study.

PLoS One · 2025 · PMC12061172 · PMID 40338907

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a decreasing trendno p-value reported

Overall, there was an increasing trend in the prescription of FXa inhibitors among the younger age groups over time in CDM, while the oldest age group (12–17 years) showed a decreasing trend.

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an increasing trendno p-value reported

The percentage of patients in the < 1-year-old age group was consistently low, but showed an increasing trend in recent years, from 1.1% in 2018 to 4.3% in 2023.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.