Global, regional, and national burden and risk factors of ischemic heart disease, 1990-2021: an analysis of the global burden of disease study.

Front Public Health · 2025 · PMC12061725 · PMID 40352854

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a decreasing trendno p-value reported

an increasing trendno p-value reported

If the EAPC and the lower limit of its 95% CI is greater than 0, it indicates an increasing trend in the ASR; if it is less than 0, it indicates a decreasing trend in the ASR.

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an overall trendno p-value reported

Supplementary Figure S4C further demonstrates the relationship between ASMR trends and SDI in these regions, and while there is an overall trend toward decline, North Africa and the Middle East, Central Asia, Eastern Europe, Central Europe, and High-Income North America continued to have higher ASMR than the expected SDI levels. 3.3.4.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.