Barely Significant
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Supraspinal kappa-opioid receptors: new therapeutic strategies for pain, pruritus, and negative emotions.

Exp Brain Res · 2025 · PMC12062100 · PMID 40338314

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highly significantno p-value reported
This finding is highly significant for the treatment of refractory pruritic disorders with multifactorial itch, such as itch associated with end-stage renal disease.

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