Trends and Projections of Early-Onset Colorectal Cancer Burden in China, 1990-2036: Findings From the Global Burden of Disease 2021 Study.

3 A study encompassing 1 922 167 CRC patients demonstrated an increasing trend in EO-CRC incidence across all five continents. 4 EO-CRC may exhibit distinct etiological factors, molecular characteristics, clinical presentations, and prognoses compared to late-onset colorectal cancer (LO-CRC). 5 EO-CRC is more frequently located in the distal colon and rectum and is mo

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A positive APC indicates an increasing trend, while a negative APC indicates a decreasing trend.

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