Barely Significant
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Analysis of the Impact of Tofacitinib Treatment on Weight and Body Mass Index in Patients With Rheumatoid Arthritis.

ACR Open Rheumatol · 2025 · PMC12062792 · PMID 40344335

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a nonsignificant trendno p-value reported
A systematic review reported that, of 13 studies evaluating changes in body weight (including 633 patients receiving bDMARDs), 8 (including 558 patients) reported significant weight gain from baseline (mean: 1.63 kg); 2 (including 24 patients) reported a nonsignificant trend toward weight gain with treatment, and 3 (including 51 patients) showed no change in body weight.

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