Insulin Resistance in Type 1 Diabetes: Pathophysiological, Clinical, and Therapeutic Relevance.

Endocr Rev · 2025 · PMC12063105 · PMID 39998445

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The intriguing results showed a modest but highly significant hyperglycemia at 4 months followed by a progressive decrease to euglycemia between 12 and 18 months of age, increasing thereafter to the previous levels of hyperglycemia from 18 months to 4 years, 2 months prior to autoantibody positivity ( 231 ).

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