Circulating immune cells exhibit distinct traits linked to metastatic burden in breast cancer.

Breast Cancer Res · 2025 · PMC12063295 · PMID 40340807

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In contrast, low-burden metastatic patients showed a systemic immune response skewed towards B cells (with immature being significant at FDR = 1 × 10 –2 ) and monocytes (with a large proportional fold change of 1.8 and near significance FDR = 6 × 10 –2 ).

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