Tie2 activity in cancer associated myofibroblasts serves as novel target against reprogramming of cancer cells to embryonic-like cell state and associated poor prognosis in oral carcinoma patients.

J Exp Clin Cancer Res · 2025 · PMC12065280 · PMID 40349056

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highly significantno p-value reported

However, TGF-CAF cocultured cancer cells (Green) had highly significant enrichment of cells with expression pattern for the basal and mesenchymal subtype genes; as shown by AUCell scores (Fig. 8 A-iv, S10B).

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