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Preliminary evaluation of a novel serotype O foot-and-mouth disease mRNA vaccine.

Front Microbiol · 2025 · PMC12067417 · PMID 40356647

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an increasing trendno p-value reported
The early stage of vaccination induced a cellular immune response in pigs, as demonstrated by the serum concentrations of three types of cytokines (IL-2, IFN-γ, and TNF-α) in the vaccine-treated group, which exhibited an increasing trend at week 2 after the first immunization and then reverted to the similar levels to that of the control group at week 4 ( Figure 5B ).

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