Global, regional, and national burden of congenital musculoskeletal and limb anomalies, 1990-2021: a systematic analysis of the global burden of disease in 2021.

Trop Med Health · 2025 · PMC12067968 · PMID 40355938

Europe PMC DOI

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a decreasing trendno p-value reported

Conversely, if both the EAPC estimate and the upper bound of its 95% CI are less than 0, the ASR is on a decreasing trend.

also in 47,180 other papers

an increasing trendno p-value reported

If both the EAPC estimate and the lower bound of its 95% CI are greater than 0, the ASR is considered to be on an increasing trend.

also in 63,971 other papers

an overall trendno p-value reported

The analysis revealed an overall trend of decreasing morbidity rates with increasing SDI levels.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.