Global, regional, and national burden of multiple myeloma from 1990 to 2021 and projections for 2040: a systematic analysis for the global burden of disease 2021 study.

All five SDI groups showed an increasing trend in ASIR (with positive EAPC values), while high-SDI regions exhibited a decreasing trend in ASDR and DALYs (with negative EAPC values) ( Table 1 and Figure 1 ), indicating a reduction in mortality and disease burden over the study period.

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