The influence of electronic AKI alert on prognosis of adult hospitalized patients: a systematic review and meta-analysis.

Crit Care · 2025 · PMC12070640 · PMID 40355901

Europe PMC DOI

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0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

a nonsignificant trendP = 0.06so close (0.05 < p ≤ 0.1)

Sensitivity analyses showed similar results using random-effects model and mortality during all-time period as primary endpoint: increased mortality with low-intensity alerts (RR 1.15; 95% CI 1.00–1.32; I 2 = 0%; P = 0.04), decreased mortality with moderate-intensity alerts (RR 0.93; 95% CI 0.90–0.97; I 2 = 0%), and a nonsignificant trend in the high-intensity group (RR 0.92; 95% CI 0.85–1.00; I 2 = 49%; P = 0.06) (Additional file 1 : Supplementary Figs. 26, 27).

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a favorable trendno p-value reported

Responses of moderate intensity enhanced the outcomes and high-intensity shows a favorable trend with limited data.

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