Molecular insights into the effects of laser-induced optical breakdown (LIOB) after 1064 nm picosecond laser irradiation using a novel melanocyte-containing 3D skin model.

Quantitative fluorescence measurement revealed a highly significant increase in MMP9 fluorescence intensity only in laser-irradiated 3D skin models that were additionally treated with the dexpanthenol-containing ointment compared to untreated controls and picosecond laser-irradiated 3D skin models without dexpanthenol-containing ointment post-treatment (Fig. 4 d).

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