Resveratrol inhibits the formation of <i>Staphylococcus aureus</i> biofilms by reducing PIA, eDNA release, and ROS production.

The inhibition curve showed that, when the RES concentration was 2ρMIC, the OD600 value exhibited a decreasing trend within 24 h, indicating that the number of bacteria showed a decreasing trend, and the trend gradually levelled off when the RES concentration was ρMIC.

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When the RES concentration was 1/2ρMIC and 1/4ρMIC, the OD600 value gradually increased after 8 h, indicating that the number of bacteria showed an increasing trend, and the number of bacteria gradually levelled off again after 24 h ( Figure 1A ).

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