Role of hyaluronic acid in the treatment of peri-implant diseases: results of a meta-analysis.

Front Oral Health · 2025 · PMC12078234 · PMID 40376205

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closest p · 1.2× alpha

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a trend towards significancep = 0.06so close (0.05 < p ≤ 0.1)

The meta-analysis for the BOP and PD subgroups showed the highest statistical significance ( p < 0.00001 and p = 0.0003, respectively), with considerable heterogeneity (I 2 = 97% and 84% respectively) and a trend towards significance for the MBL subgroup ( p = 0.06), although with moderate heterogeneity (I 2 = 59%) ( Figures 2 – 5 ).

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