PU.1 dictates β-amyloid-induced TREM2 expression upregulation in microglia in a transgenic model of Alzheimer's disease.

Front Aging Neurosci · 2025 · PMC12078285 · PMID 40376093

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an increasing trendno p-value reported

Compared to control cells, BV2 cells with PU.1 overexpression exhibited an increasing trend in Aβ phagocytosis efficiency, Nile red fluorescent microsphere phagocytosis efficiency, and the percentage of phagocytic cells.

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