Barely Significant
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Global, regional, and national trends in tobacco-induced cardiovascular disease burden for 1990-2021 with projections to 2045: A comprehensive analysis based on the Global Burden of Disease Study 2021.

Tob Induc Dis · 2025 · PMC12080230 · PMID 40376198

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an increasing trendno p-value reported
However, individuals aged ≥80 years showed an increasing trend in mortality rates (Supplementary file Figure 5).

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