Barely Significant
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An Extracellular Matrix Hydrogel Restores Disc Volume and Alleviates Axial Hypersensitivity in a Rat Model of Disc-Associated Pain.

JOR Spine · 2025 · PMC12081325 · PMID 40386495

3
hedged sentences
0.0029
closest p · 0.1× alpha
0.0670
boldest claim

The sentences

highly significantp < 0.0029actually significant
Intriguingly, dNP+ animals traveled significantly more than both PBS and sham animals, and this effect was highly significant ( p < 0.0029 dNP+ vs. sham, p < 0.0006 dNP+ vs.

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a trend toward significancep < 0.052so close (0.05 < p ≤ 0.1)
Analysis of the cell counts indicated that dNP+ proliferation was 76% of the collagen control and it did not significantly decrease cellular proliferation compared to collagen + dNP, although there was a trend toward significance ( p < 0.052, Figure 4G ).

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narrowly missed significancep = 0.067so close (0.05 < p ≤ 0.1)
Similarly, the relationship between total PGP+ area and normalized grip strength values narrowly missed significance ( p = 0.067) (Figure S2C ). 3.12. dNP+ Confounds Several Relationships Between Assessed Metrics A correlation matrix was created to identify significant relationships existing between study metrics for all animals (sham, injured, dNP+) or just sham and injured animals (Figure S3A,B ).

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