Trends in the incidence of common sexually transmitted infections at the global, regional and national levels, 1990-2021: results of the Global Burden of Disease 2021 study.

In contrast, when ASIR exceeds 12,500, EAPC consistently shows a decreasing trend ( P = 6.04e−75, R 2 = 0.1546).

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In contrast, the ASRs for syphilis and chlamydia demonstrated an increasing trend, with the most significant rise in chlamydia ASRs observed in the Maldives, followed by the Cook Islands and Colombia.

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The rate of DALYs for STIs peaks between the ages of 30 and 40 years, exhibiting an overall trend of increase followed by a decrease (Fig. 8 ; Table S5).

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