Effector T cells under hypoxia have an altered transcriptome similar to tumor-stressed T cells found in non-responsive melanoma patients.

J Immunother Cancer · 2025 · PMC12086921 · PMID 40010774

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantp<2.2e−16actually significant

Statistical analyses showed that Pearson’s χ 2 test with Yates’ continuity correction had a χ 2 statistic of 34,319 with 1 df, indicating a highly significant association (p<2.2e−16).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.