Bugbase phenotype prediction highlighted a gradual increase in Gram-negative bacteria, potentially pathogenic, facultatively anaerobic, and stress-tolerant species in the control, IR, and AKK groups, whereas Gram-positive bacteria showed a decreasing trend ( Figs 3F and S2B ).
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Akkermansia muciniphila exacerbates acute radiation-induced intestinal injury by depleting mucin and enhancing inflammation.
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