Functional assessment of coronary stenosis: alternative hyperemic, nonhyperemic, and angiographic indexes.

21 Outcome data Two large randomized trials (DEFINE-FLAIR, n = 2492; iFR-SWEDEHEART, n = 2037) showed the noninferiority of an iFR vs an FFR-guided PCI strategy during follow-up at 1 year and 5 years, although iFR showed lower revascularization rates with almost significant P values. 31 , 32 The rate of major adverse cardiac events (MACE) were 18.6% (iFR) vs 16.8% (FFR) ( P = .63) after 5 years in deferred patients who presented with stable angina (n = 611) or nonculprit lesions of ACS (unstable angina and NSTEMI, n = 297).

also in 511 other papers