T-follicular helper cell profiles differ by malaria antigen and for children compared to adults.

Elife · 2025 · PMC12097790 · PMID 40402846

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highly significantno p-value reported

In our study, Pf GARP induced a highly significant increase of Bcl6 in cT FH 2-like and cT FH 17-like subsets in children, suggesting that Pf GARP may be a better candidate to trigger an efficient humoral response in children compared to Pf SEA-1A.

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