Novel neoadjuvant therapies for muscle-invasive bladder cancer: Systematic review and meta-analysis.

19 The association between TMB and treatment response was evaluated in two studies with 121 patients, with a nonsignificant trend suggesting potential benefit in high TMB status (OR, 2.17; 95% CI, 0.51–9.17; P = 0.29; I 2 = 56%) (Figure 4B ).

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