Structural and Functional Analysis of the Human IQSEC2 S1474Qfs*133 Mutation.

Figure 5 shows that there was a highly significant reduction in weight in the male S1474Qfs*133 male mice as compared to their wild-type male littermates (N = 3–6 mice at each time point for each genotype measured through 20 days of age). 3.5.

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