CXCR Family and Hematologic Malignancies in the Bone Marrow Microenvironment.

Biomolecules · 2025 · PMC12109521 · PMID 40427609

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may not be significantno p-value reported

[ 126 ] used CXCR4[ 68 Ga]Ga-PentixaFor PET/CT imaging to detect the potential “lymphoma sink effect” in patients with marginal zone lymphoma (MZL), but unfortunately, this study showed no association between normal organ uptake and the CXCR4-positive lymphoma burden in MZL patients, suggesting that the lymphoma sink effect of MZL may not be significant relative to other therapeutic radiotracers used for the imaging and treatment of solid tumors.

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an increasing trendno p-value reported

In recent years, the incidence of MM has shown an increasing trend year by year, and it is currently the second most common hematologic tumor after NHL.

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