Understanding ROS regulation is highly significant since ROS modulation influences the outcome of common cancer therapies such as radio and chemotherapy drugs [ 51 ].
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The Use of Mutational Signatures to Decipher the Inter-Relationship of Reactive Oxygen Species with Homologous Recombination and Non-Homologous End-Joining Deficiencies as Well as Their Effects on APOBEC Mutagenesis in Breast Cancer.
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