Barely Significant
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The Regulation of the NF-κB p65 and Nrf2/HO-1 Signaling Pathways by Fucoxanthin in Human THP-1 Monocyte Macrophages Under a Lipopolysaccharide-Induced Inflammation Model.

Foods · 2025 · PMC12110976 · PMID 40428524

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highly significantno p-value reported
When the concentration of fucoxanthin was 0.1 and 1 μg/mL, it had a highly significant inhibitory effect on COX-2 in cells.

also in 132,142 other papers

a decreasing trendno p-value reported
With the increase of fucoxanthin concentration, the cell viability of THP-1 showed a decreasing trend.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.