Single Injection of Highly Concentrated Hyaluronic Acid Provides Improvement of Knee Joint Arthrokinematic Motion and Clinical Outcomes in Patients with Osteoarthritis-Non-Randomized Clinical Study.

J Clin Med · 2025 · PMC12112193 · PMID 40429552

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Introduction Patients with knee osteoarthritis (OA) represent a highly significant number of people in orthopedic healthcare who require a functioning therapy, as it is estimated that up to 25% of adults experience frequent knee pain related to the chronic process destroying the normal structure of the joint [ 1 , 2 ].

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