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Plasma Dickkopf-1 Levels Are Associated with Chronic Kidney Disease.

Metabolites · 2025 · PMC12112992 · PMID 40422877

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an increasing trendno p-value reported
CKD has been a heavy burden on global health in the past 30 years, with an increasing trend of mortality and disability resulting from CKD [ 1 , 2 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.