Development of New Live-Attenuated Vaccine Candidates Lacking Antibody-Dependent Enhancement (ADE) Against Dengue.

Vaccines (Basel) · 2025 · PMC12115996 · PMID 40432141

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an increasing trendno p-value reported

In this study, 3 years after receiving the CYD-TDV vaccine, there was an increasing trend in hospitalisation risk for the vaccinees, especially among the dengue-seronegative vaccinees, suggesting that the vaccine was far more suitable for dengue-seropositive vaccinees in terms of superior efficacy and beneficial vaccine effect [ 42 , 43 ].

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