DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.

NPJ Dement · 2025 · PMC12116384 · PMID 40443531

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hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a trend towards significancep = 0.06so close (0.05 < p ≤ 0.1)

There was also a trend towards significance for DNAmGrimAge (HR 1.03; 95% CI 1.00–1.06; p = 0.06) (Fig. 1 ).

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