IL-13 May Could Enhance the Proliferation and Affect the Differentiation of Nasal Epithelium Basal Cells Through the mTOR/p70S6K1 Pathway in Chronic Rhinosinusitis With Nasal Polyps.

The results indicated that protein expression level the of p-mTOR, p-p70S6K1, P63, Ki67, cyclin E1, and CDK2 were increased in the IL-13 group and have statistical meaning ( Figure 4 A,C,E–I, p < 0.05), mTOR and p70S6K1 in HNESPCs were not over-expressed after the stimulation of IL-13, but have an increasing trend ( Figure 4 A,B, and D, p > 0.05).

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