Disentangling the divergent causal pathways underlying the association between body mass index and bone mineral density: a comprehensive Mendelian randomization study.

BMC Med · 2025 · PMC12121138 · PMID 40437494

Europe PMC DOI

hedged sentence

0.0498

closest p · 1.0× alpha

0.0498

boldest claim

The sentences

marginally significantP value = 4.98 × 10 −2actually significant

Notably, the protective association between skeletal muscle-tissue instrumented BMI and eBMD remained marginally significant and attenuated slightly when adjusting for visceral adipose-tissue instrumented BMI ( β IVW = 0.14, 95%CIs = 0.00 ~ 0.28, P value = 4.98 × 10 −2 , Fig. 4 ).

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