Barely Significant
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A pragmatic, multicenter, randomized trial comparing morning versus evening dosing of adjuvant endocrine therapy (REaCT-CHRONO Study).

NPJ Breast Cancer · 2025 · PMC12122688 · PMID 40442096

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a slight trendno p-value reported
Also, we evaluated the association between higher stage and adherence and found no statistically significant difference by stage, although there was a slight trend of higher adherence with higher stage ( p -values 0.53 and 0.49 at 12 weeks and 52 weeks, respectively).

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