Barely Significant
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The pharmacokinetics, pharmacodynamics and tolerability of SHR6508 in chinese healthy subjects: a randomized, placebo-controlled, double-blind, single-dose and dose-escalation phase I trial.

Naunyn Schmiedebergs Arch Pharmacol · 2025 · PMC12125103 · PMID 39680101

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a decreasing trendno p-value reported
In this study, FGF23 showed a decreasing trend after administration, but no significant dose-dependent dependence was seen.

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